Product Metrics for the Manufacturability of Single-Crystal Gold Nanorods via Reaction Engineering.

Colloidal gold nanorods (AuNRs) are integral to a diverse array of technologies, ranging from plasmonic imaging, therapeutics, and sensors to large-area coatings, catalysts, filters, and optical attenuators. Different lab-scale strategies are available to fabricate AuNRs with a broad range of physiochemical properties; however, this is achieved at the cost of synthetic robustness and scalability, which limit broad adoption in these technologies. To address this, Product Metrics (Structural Precision, Shape Yield, and Reagent Utilization), measurable with UV-vis-NIR spectroscopy, are defined to evaluate the efficiency of AuNR production.