Spironolactone and topical retinoids in adult female cyclical acne.

Purpose: To access the efficacy of spironolactone and topical retinoids in the treatment of female cyclical acne.

Methods: A retrospective chart review on 41 female patients age 19-57 years old with cyclical acne was performed. Patients were examined over the course of 2 to 102 months while taking 50 to 200 mg of spironolactone and topical tretinoin 0.