Publications by authors named "Michael N Megafu"
Article Synopsis
- Reverse total shoulder arthroplasty (RTSA) is often evaluated using patient-reported outcome measures (PROMs) and relies on metrics like minimum clinically important difference (MCID) and substantial clinical benefit (SCB) to determine its effectiveness.
- A systematic review analyzed 141 articles from various medical databases, ultimately including 39 studies with data on 11,984 patients who underwent RTSA, focusing on different thresholds used for MCID, SCB, patient acceptable symptom state (PASS), and maximal outcome improvement (MOI).
- Findings showed significant variability in reported MCID and SCB values across studies, highlighting the need for more standardized methods in calculating and applying these thresholds to improve clinical assessment of RTSA outcomes.
Article Synopsis
- This study analyzes the robustness of cervical disc arthroplasty (CDA) literature by using the fragility index (FI) and fragility quotient (FQ) to evaluate statistical vulnerability in outcomes.
- A comprehensive PubMed search identified 35 randomized controlled trials (RCTs) from 2000 to 2023, revealing 693 outcome events, of which 130 were statistically significant.
- Findings indicate a lack of statistical robustness in CDA studies, as many did not adequately report loss to follow-up data, suggesting that relying solely on P values could misrepresent clinical conclusions.
Over the past decade, the American Association of Colleges of Osteopathic Medicine (AACOM) and the Association of American Medical Colleges (AAMC) have emphasized the need to enhance diversity within medical education. Despite concerted efforts, the representation of underrepresented populations in medicine (URiM), particularly Black men, remains alarmingly low. This commentary delves into the persisting challenges and potential solutions surrounding the lack of diversity of Black men in osteopathic schools.
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- The study evaluated the statistical stability of outcomes from randomized controlled trials (RCTs) focusing on the management of femoral neck fractures, using metrics like fragility index (FI), reverse fragility index (rFI), and fragility quotient (FQ).
- After screening 985 articles, 71 studies were analyzed, revealing a median FI of 4, indicating that a small number of event reversals could change the statistical significance of findings.
- The results suggest that many outcomes in these RCTs are fragile, prompting the authors to recommend standardized reporting of P-values to improve the reliability of the data.
Background: Reverse total shoulder arthroplasty (RTSA) has seen increasing utilization as an effective intervention for a wide variety of shoulder pathologies. The scope and indications for growth are often driven by findings from randomized controlled trials (RCTs) guiding surgical decision-making for RTSA. In this study, we utilized the fragility index (FI), reverse fragility index (rFI), and fragility quotient (FQ) to assess the robustness of outcomes reported in RCTs in the RTSA literature.
View Article and Find Full Text PDFBackground: The purpose of this present study was to perform a fragility analysis to assess the robustness of randomized controlled trials (RCTs) evaluating the distal biceps tendon repairs. We hypothesize that the dichotomous outcomes will be statistically fragile, and higher fragility will exist among statistically significant outcomes comparable to other orthopedic specialties.
Methods: Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), randomized controlled trials from 4 orthopedic journals indexed on PubMed from 2000 to 2022 reporting dichotomous measures relating to distal biceps tendon repairs were included.
Background: The P value has often been used as a tool to determine the statistical significance and evaluate the statistical robustness of study findings in orthopedic literature. The purpose of this study is to apply both the fragility index (FI) and the fragility quotient (FQ) to evaluate the degree of statistical fragility in orbital fracture literature. We hypothesized that the dichotomous outcomes within the orbital fracture literature will be vulnerable to a small number of outcome event reversals and will be statistically fragile.
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