Publications by authors named "Michael N Le"
Many central nervous system (CNS) disorders lack approved treatment options. Previous research demonstrated that peptide CAQK can bind to chondroitin sulfate proteoglycans (CSPGs) in the extracellular matrix of the CNS. In vivo studies have investigated CAQK conjugated to nanoparticles containing therapeutic agents with varying methodologies/outcomes.
View Article and Find Full Text PDFArticle Synopsis
- Healthspan science focuses on increasing the number of healthy years in a person's life by investigating various methods to improve overall health and longevity.
- Research has shown that returning to ancestral diets can enhance functional health in older individuals and that certain botanical extracts may significantly extend lifespan without affecting reproductive ability.
- This study explores the combined effects of an ancestral diet and botanical extracts, finding that while one extract improved health, another had negative effects when paired with the diet, highlighting the need for further research on how different healthspan interventions interact.