Publications by authors named "Michael Lujan"
Article Synopsis
- - NASA's OSIRIS-REx mission successfully collected a sample from asteroid Bennu in October 2020, with plans to deliver it to Earth in September 2023, despite challenges in finding suitable collection sites due to unexpected surface conditions.
- - A "Sampleability Map" was created to identify and evaluate potential sampling locations on Bennu based on how compatible they were with the spacecraft's sampling mechanism, using a scoring system called "sampleability."
- - The sampleability algorithm assessed surface properties on two levels: globally to understand Bennu's surface as a whole and site-specifically for higher-resolution predictions at targeted collection spots, ultimately aiding in choosing the optimal collection location.
The global epidemic of diabetes mellitus (~95% type 2 diabetes) has been fueled by a parallel increase in obesity and overweight. Together, these metabolic disease epidemics have contributed to the increasing incidence and prevalence of cardiovascular disease. The accumulation of metabolic and cardiovascular risk factors in patients with type 2 diabetes--risk factors that may exacerbate one another--complicates treatment.
View Article and Find Full Text PDFRecent studies have failed to show an improvement in cardiovascular mortality with intensive glycemic control and aggressive glycated hemoglobin (A(1c)) targets less than 7.0%. Excessive hypoglycemic episodes with intensive glucose-lowering therapy are thought to be a major factor in the failure to show cardiovascular benefit in these trials.
View Article and Find Full Text PDFThe effect of thiazolidinediones (TZDs) on the progression of atherosclerosis in diabetes patients remains unclear. There has been heightened interest in recent years in this class of diabetes medications due to the non-glycemic lowering effects, such as altering lipids, inflammation and hematologic profiles. There have been several exciting studies over the past few years focused on the mechanism of action of the TZDs with respect to alteration in the cardio-metabolic profile in diabetes patients.
View Article and Find Full Text PDFAortic stenosis catheterization revisited: a long sheath single-puncture technique.
J Invasive Cardiol
June 2006
Objectives: To evaluate the accuracy of a new long sheath single-puncture technique in obtaining accurate transvalvular gradients in aortic stenosis.
Background: Despite advances in echo Doppler, the evaluation of aortic stenosis continues to be a common procedure in the cardiac catheterization laboratory. Experts agree that simultaneous evaluation of the proximal aortic and left ventricular pressures yields the most accurate data; however, this is difficult to achieve unless two arterial punctures are performed.