Publications by authors named "Michael Lintner-Rivera"
Article Synopsis
- The study aimed to evaluate the relationship between the perfusion index (PI), a noninvasive tool, and clinical markers of perfusion in critically ill children hospitalized with severe malaria, investigating its potential to identify those at higher risk of mortality.
- Conducted in two hospitals in Uganda, the research analyzed data from 600 children under five with severe malaria and found that lower admission PI correlated with clinical signs of poor perfusion and complications, as well as higher mortality odds.
- The results indicated that consecutive low PI measures (< 1%) were predictive of mortality, suggesting that PI could serve as an important indicator for managing severe malaria in pediatric patients.
The true global burden of paediatric critical illness remains unknown. Studies on children with life-threatening conditions are hindered by the absence of a common definition for acute paediatric critical illness (DEFCRIT) that outlines components and attributes of critical illness and does not depend on local capacity to provide critical care. We present an evidence-informed consensus definition and framework for acute paediatric critical illness.
View Article and Find Full Text PDFBackground: Acute kidney injury is common in severe malaria and is independently associated with mortality. The pathogenesis of acute kidney injury (AKI) in severe malaria remains incompletely understood. Ultrasound-based tools such as point-of-care ultrasound (POCUS), ultrasound cardiac output monitors (USCOMs) and renal arterial resistive index (RRI) can be used to detect hemodynamic and renal blood flow abnormalities contributing to AKI in malaria.
View Article and Find Full Text PDF