Predictive relevance of clinical scores and inflammatory parameters in secondary peritonitis.

Hypothesis: To measure and evaluate clinical scores and various inflammation parameters for providing a better outcome assessment of patients with secondary peritonitis.

Design: Prospective study.

Setting: ICU of a university and a university affiliated hospital.

Circulating mediators and organ function in patients undergoing planned relaparotomy vs conventional surgical therapy in severe secondary peritonitis.

Hypothesis: Planned relaparotomy (PRL) has been suggested to have detrimental effects on the systemic activation of inflammation mediators, thereby enhancing organ dysfunctions as assessed by clinical scores in secondary peritonitis.

Design: Prospective, nonrandomized control trial.

Setting: Intensive care units of an urban and a university teaching hospital.