The "Cone-Head" sign: Magnetic resonance image findings of the "Headspin Hole", an overuse injury found in breakdancers.

Breakdancing can cause the formation of a painless lump on the scalp at the vertex of the skull, with associated hair loss called a "Headspin Hole." This occurs secondary to chronic inflammation from performing spinning dance moves on the head. We present the radiological findings of the "Headspin Hole" in a 38-year-old male with a history of breakdancing.

The integration of process analytical technologies, concurrent validation, and parametric release programs in aseptic processing: Parenteral Drug Association.

Approaches such as process analytical technology (PAT), concurrent validation, and parametric release have a common purpose. The purpose is to improve product and process quality control by monitoring and utilizing on-line and in-line measurements at critical controls points and phases in the manufacturing operation. This paper discusses how the integration of PAT, concurrent validation, and parametric release programs (collectively referred to as "quality enhancement programs") can be used to improve product quality during manufacturing, and can result in economic and efficiency improvements for the industry.