1.5-Stage Revision for the Treatment of Periprosthetic Joint Infection: A Systematic Review.

Introduction: Although the two-stage exchange has been the gold standard for the treatment of periprosthetic joint infection (PJI), there is recent data to suggest that the utilization of a well-functioning destination spacer, also known as a "functional" or "1.5-stage revision," can be a viable treatment option in patients who have a PJI. The purpose of this systematic review was to evaluate the outcomes of patients undergoing a 1.

Clinical and Personal Lubricants Impact the Growth of Vaginal Lactobacillus Species and Colonization of Vaginal Epithelial Cells: An in Vitro Study.

Background: Vaginal lubricants are commonly used during gynecological examinations, during sexual activities, or to alleviate vaginal dryness. Many lubricants contain potentially bacteriostatic or bactericidal agents (parabens, chlorhexidine gluconate, nonoxynol-9). Our objective was to evaluate the impact of lubricants that vary in formulation on the growth and viability of vaginal Lactobacillus species and vaginal epithelial cell (VEC) colonization in an in vitro model.