Do Prenatal Corticosteroids Affect Brain Maturation of the Premature Infant? An Electroencephalography Study.

Objective: To assess whether prenatal treatment with betamethasone has a significant influence on cerebral maturation indices as measured by electroencephalographic (EEG) indices.

Study Design: Infants born less than 35 weeks postmenstrual age (PMA) were prospectively enrolled if their mother received a full course of bethametasone prior to delivery (study group) or not (control group); infants with major intracranial abnormalities were excluded as well as those who were sedated or needed assisted ventilation. EEG was recorded during the first 10 days of life.

Description and evaluation of a clerkship in International Health and Medicine.

Background And Objectives: In 1998 Ben-Gurion University, in collaboration with Columbia University, inaugurated the first medical school with the express purpose of training students in International Health and Medicine (IHM). The highlight of the program is the two-month clerkship in IHM. The purpose of this paper is to describe the IHM clerkship and report the preliminary results of an evaluation.

Predictive value of amplitude-integrated electroencephalography pattern and voltage in asphyxiated term infants.

The aim of this study was to correlate amplitude-integrated electroencephalography soon after birth with neurodevelopmental outcome in children who suffered from hypoxic-ischemic encephalopathy. Near term infants with hypoxic-ischemic encephalopathy and amplitude-integrated electroencephalography recording before 6 hours of age were included. Neurologic and cognitive outcome were assessed at 30 months of age and over.

Amplitude-integrated electroencephalography: a tool for monitoring silent seizures in neonates.

The clinical use of amplitude-integrated electroencephalography in the diagnosis of seizures in high-risk newborn infants with suspected central nervous system insult is evaluated with emphasis on silent seizures. Recordings from 93 infants with suspected central nervous system insults over a period of 7 years were retrospectively analyzed for the presence of electrical seizures and for their correlation with clinical events. Thirty infants (32%) had overt clinical seizures; 29 (97%) of these manifested clear seizure patterns in their tracings, and the remaining one infant had a suspected tracing.

Infective endocarditis successfully treated in extremely low birth weight infants with recombinant tissue plasminogen activator.

Increased survival of extremely low birth weight infants depends on the use of indwelling catheters. These catheters expose the infant to the risk of thrombus formation and line infection. When intracardiac thromboses become infected, the entity is indistinguishable from infective endocarditis and exposes the infant to prolonged sepsis and risk of disseminated infected emboli.