Publications by authors named "Michael Kampffmeyer"

Article Synopsis
  • - The study focuses on developing a non-invasive deep-learning model (DLIF) that predicts a usable input function for dynamic positron emission tomography (PET) in small animal research, specifically mice, without needing arterial blood sampling.
  • - The DLIF model was trained on 68 mouse scans and tested against an external dataset of 8 scans, showing similar results to traditional methods, although some discrepancies were noted due to differences in experimental setups.
  • - The findings suggest that the DLIF method could replace the complex and invasive arterial cannulation process, enabling more comprehensive and repeated PET imaging studies in mice.
View Article and Find Full Text PDF

Deep generative models with latent variables have been used lately to learn joint representations and generative processes from multi-modal data, which depict an object from different viewpoints. These two learning mechanisms can, however, conflict with each other and representations can fail to embed information on the data modalities. This research studies the realistic scenario in which all modalities and class labels are available for model training, e.

View Article and Find Full Text PDF

In recent years, the prediction of quantum mechanical observables with machine learning methods has become increasingly popular. Message-passing neural networks (MPNNs) solve this task by constructing atomic representations, from which the properties of interest are predicted. Here, we introduce a method to automatically identify chemical moieties (molecular building blocks) from such representations, enabling a variety of applications beyond property prediction, which otherwise rely on expert knowledge.

View Article and Find Full Text PDF

A major barrier to applying deep segmentation models in the medical domain is their typical data-hungry nature, requiring experts to collect and label large amounts of data for training. As a reaction, prototypical few-shot segmentation (FSS) models have recently gained traction as data-efficient alternatives. Nevertheless, despite the recent progress of these models, they still have some essential shortcomings that must be addressed.

View Article and Find Full Text PDF

Analyzing deep neural networks (DNNs) via information plane (IP) theory has gained tremendous attention recently to gain insight into, among others, DNNs' generalization ability. However, it is by no means obvious how to estimate the mutual information (MI) between each hidden layer and the input/desired output to construct the IP. For instance, hidden layers with many neurons require MI estimators with robustness toward the high dimensionality associated with such layers.

View Article and Find Full Text PDF

Deep learning-based approaches for content-based image retrieval (CBIR) of computed tomography (CT) liver images is an active field of research, but suffer from some critical limitations. First, they are heavily reliant on labeled data, which can be challenging and costly to acquire. Second, they lack transparency and explainability, which limits the trustworthiness of deep CBIR systems.

View Article and Find Full Text PDF

Data government has played an instrumental role in securing the privacy-critical infrastructure in the medical domain and has led to an increased need of federated learning (FL). While decentralization can limit the effectiveness of standard supervised learning, the impact of decentralization on partially supervised learning remains unclear. Besides, due to data scarcity, each client may have access to only limited partially labeled data.

View Article and Find Full Text PDF

Image translation with convolutional autoencoders has recently been used as an approach to multimodal change detection (CD) in bitemporal satellite images. A main challenge is the alignment of the code spaces by reducing the contribution of change pixels to the learning of the translation function. Many existing approaches train the networks by exploiting supervised information of the change areas, which, however, is not always available.

View Article and Find Full Text PDF

Recent work has shown that label-efficient few-shot learning through self-supervision can achieve promising medical image segmentation results. However, few-shot segmentation models typically rely on prototype representations of the semantic classes, resulting in a loss of local information that can degrade performance. This is particularly problematic for the typically large and highly heterogeneous background class in medical image segmentation problems.

View Article and Find Full Text PDF

Deep learning-based support systems have demonstrated encouraging results in numerous clinical applications involving the processing of time series data. While such systems often are very accurate, they have no inherent mechanism for explaining what influenced the predictions, which is critical for clinical tasks. However, existing explainability techniques lack an important component for trustworthy and reliable decision support, namely a notion of uncertainty.

View Article and Find Full Text PDF

Age-reading of fish otoliths (ear stones) is important for the sustainable management of fish resources. However, the procedure is challenging and requires experienced readers to carefully examine annual growth zones. In a recent study, convolutional neural networks (CNNs) have been demonstrated to perform reasonably well on automatically predicting fish age from otolith images.

View Article and Find Full Text PDF

Colorectal polyps are known to be potential precursors to colorectal cancer, which is one of the leading causes of cancer-related deaths on a global scale. Early detection and prevention of colorectal cancer is primarily enabled through manual screenings, where the intestines of a patient is visually examined. Such a procedure can be challenging and exhausting for the person performing the screening.

View Article and Find Full Text PDF

A promising direction in deep learning research consists in learning representations and simultaneously discovering cluster structure in unlabeled data by optimizing a discriminative loss function. As opposed to supervised deep learning, this line of research is in its infancy, and how to design and optimize suitable loss functions to train deep neural networks for clustering is still an open question. Our contribution to this emerging field is a new deep clustering network that leverages the discriminative power of information-theoretic divergence measures, which have been shown to be effective in traditional clustering.

View Article and Find Full Text PDF

Salient segmentation aims to segment out attentiongrabbing regions, a critical yet challenging task and the foundation of many high-level computer vision applications. It requires semantic-aware grouping of pixels into salient regions and benefits from the utilization of global multi-scale contexts to achieve good local reasoning. Previous works often address it as two-class segmentation problems utilizing complicated multi-step procedures including refinement networks and complex graphical models.

View Article and Find Full Text PDF