Publications by authors named "Michael Joseph Miller"
Article Synopsis
- The combination of Conjugated Estrogens (CE) and Bazedoxifene (BZA) aims to relieve menopause symptoms in women but its effects on gut microbiome and enzyme activity have not been previously studied.
- A mouse study revealed that while CE+BZA didn't significantly alter the overall gut microbiome, it did reduce the abundance of Akkermansia, associated with weight gain, and lowered fecal GUS activity linked to Lactobacillaceae abundance.
- This research suggests that long-term estrogen supplementation can directly influence gut microbial activity and composition, potentially optimizing the metabolism of estrogens for better health outcomes in postmenopausal women or breast cancer patients.
