Publications by authors named "Michael Jaeger Wanscher"
BACKGROUND: The evidence for temperature control for comatose survivors of cardiac arrest is inconclusive. Controversy exists as to whether the effects of hypothermia differ per the circumstances of the cardiac arrest or patient characteristics. METHODS: An individual patient data meta-analysis of the Targeted Temperature Management at 33°C versus 36°C after Cardiac Arrest (TTM) and Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trials was conducted.
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- Arginine vasopressin and its marker, copeptin, play significant roles in the prognosis of critically ill patients, especially post-cardiac arrest, affecting factors like plasma volume and cortisol levels.
- The study analyzed 690 patients who survived out-of-hospital cardiac arrest, measuring copeptin at 24, 48, and 72 hours, focusing on its correlation with 30-day survival and cardiovascular deterioration.
- Results showed that higher levels of copeptin at 24 hours were linked to better survival rates and lower risk of cardiovascular issues, implying it could serve as an important marker for assessing post-cardiac arrest severity.
Purpose: This study investigates the association between mean arterial pressure (MAP) and renal function after out-of-hospital cardiac arrest (OHCA).
Materials And Methods: Post-hoc analysis of 851 comatose OHCA-patients surviving >48 h included in the targeted temperature management (TTM)-trial.
Results: Patients were stratified by mean MAP during TTM in the following groups; <70 mmHg (22%), 70-80 mmHg (43%), and > 80 mmHg (35%).
Background: To evaluate if an opiate sparing multimodal regimen of dexamethasone, gabapentin, ibuprofen and paracetamol had better analgesic effect, less side effects and was safe compared to a traditional morphine and paracetamol regimen after cardiac surgery.
Methods: Open-label, prospective randomized controlled trial. 180 patients undergoing cardiac procedures through median sternotomy, were included in the period march 2007-August 2009.