Publications by authors named "Michael J Hershman"

Article Synopsis
  • A watch and wait strategy after chemoradiotherapy for rectal cancer offers a potential way to avoid surgery, but one-third of tumors may regrow, necessitating further surgical intervention.
  • This study evaluated the effectiveness of contact X-ray brachytherapy (CXB) in preserving organs and reducing the need for surgery in patients with a clinical complete response (cCR).
  • Results showed that CXB led to a lower local regrowth rate of 11% and a 62% organ preservation rate, indicating it could be a valuable option for patients not wanting or able to undergo surgery.
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An elderly woman presented with abdominal pain and vomiting, was known to have gallstones. A CT scan was arranged identifying gallstone ileus and cholecystitis. Ensuing sepsis precipitated fast atrial fibrillation delaying the planned laparotomy.

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Intestinal epithelial cells migrate from the base of the crypt to the villi where they are shed. However, little is known about the cell shedding process. We have studied the role of apoptosis and wound healing mechanisms in cell shedding from human small intestinal epithelium.

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Therapy for adhesions encompasses their prevention and treatment. They are reduced in number and severity by good surgical technique but anti-adhesion agents are useful adjuncts. Small bowel obstruction secondary to adhesions requires surgery following resuscitation if signs of peritonism develop.

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Laparoscopic surgery for inflammatory bowel disease is an expanding field, which has physical benefits to the patient and economic benefits to the trust and community.

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Ulcerative colitis is potentially cured by total excision of the colon and rectum. Crohn's disease is an unremitting condition in which operations are frequently multiple and in which the minimum amount of bowel possible should be excised.

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Stapled haemorrhoidectomy is an effective procedure for symptomatic haemorrhoids with mucosal prolapse. The advantages over the conventional surgical technique include reduced postoperative pain, shorter hospital stay and earlier return to work.

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The follow up of patients after colorectal cancer surgery remains controversial. It may be intensive or minimal. The authors describe an intensive follow-up regimen and discuss the leading role of the colorectal specialist nurse.

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This study assesses the practicality, mortality and morbidity of the STAR procedure for debulking of large rectal tumours prior to transanal endoscopic microsurgery.

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