Effects of outdoor weathering and laundering on the detection and classification of fluorinated oil-and-water-repellent fabric coatings.

Fluorinated polymer coatings are used to impart durable oil-and-water-repellent properties on fabrics, potentially offering a persistent fiber characteristic for forensic fiber comparisons. To evaluate the persistence of these coatings, we investigate effects of outdoor weathering and laundering on detection and classification of the fluorinated oil-and-water-repellent coatings on 9 garments and 2 spray-coated fabric samples. Single fibers from the samples are pyrolyzed and subjected to gas chromatography coupled to a fluorine-selective detector.

Detection and diversity of fluorinated oil- and water-repellent coatings on apparel fibers.

Fluorinated coatings, often used for oil and water repellency and stain resistance in fabrics, are potentially persistent forensic fiber markers. However, they have received limited attention because of challenges in their detection caused by the small size of a single fiber and thin nature of stain-resistant coatings. Here, we utilize a sensitive fluorine-selective analytical technique to detect and evaluate diversity of fluorinated coatings in apparel.

Elemental Fluorine Detection by Dielectric Barrier Discharge Coupled to Nanoelectrospray Ionization Mass Spectrometry for Nontargeted Analysis of Fluorinated Compounds.

The growing use of fluorochemicals has elevated the need for nontargeted detection of unknown fluorinated compounds and transformation products. Elemental mass spectrometry (MS) coupled to chromatography offers a facile approach for such analyses by using fluorine as an elemental tag. However, efficient ionization of fluorine has been an ongoing challenge.

Classifying single fibers based on fluorinated surface treatments.

Fibers are an important form of forensic evidence, but their evidential value can be severely limited when the identified characteristics of the fibers are common, such as blue cotton. Detecting chemical fiber treatments offers an avenue to further classify fibers and to improve their evidential value. In this report, we investigate the potential of fluoropolymer fiber coatings, used to impart oil and water-repellent properties in fabrics, for differentiating between fibers.

Diabetes Mellitus-Not Just Type 1 or Type 2 Anymore.

Introduction: Diabetes mellitus traditionally has been categorized as type 1 (insulin deficiency due to autoimmune destruction of islet cells) or type 2 (insulin resistance with the development of relative insulin deficiency). However, other pathophysiologic etiologies for diabetes must be considered in the evaluation of patients with new-onset diabetes.

Case Presentation: We report the case of a 50-year-old man with a diagnosis of type 2 diabetes mellitus who-despite appropriate pharmacotherapy-developed worsening hyperglycemia.

Atrioesophageal Fistula: A Rare Complication of Radiofrequency Ablation.

75-year-old woman was admitted with fever, chills, altered mentation, and right-sided weakness. A month earlier, she had undergone catheter radiofrequency ablation for treatment of chronic atrial fibrillation. A magnetic resonance imaging scan of her brain revealed septic emboli with multiple bilateral cerebral and cerebellar infarcts, as well as extensive bilateral leptomeningeal enhancement.

Atmospheric-Pressure Dielectric Barrier Discharge as an Elemental Ion Source for Gas Chromatographic Analysis of Organochlorines.

Atmospheric-pressure dielectric barrier discharge (AP-DBD) plasma has emerged in recent years as a versatile plasma for molecular ionization and elemental spectroscopy. However, its capabilities as an elemental ion source have been less explored, partly because of difficulties in the detection of positive elemental ions from this low-gas-temperature plasma. In this work, we investigate the detection of negative elemental ions to enable elemental mass spectrometry (MS) using AP-DBD.

Comparison of seating, powered characteristics and functions and costs of electrically powered wheelchairs in a general population of users.

Purpose: To profile and compare the seating and powered characteristics and functions of electrically powered wheelchairs (EPWs) in a general user population including equipment costs.

Method: Case notes of adult EPW users of a regional NHS service were reviewed retrospectively. Seating equipment complexity and type were categorized using the Edinburgh classification.

Control devices for electrically powered wheelchairs: prevalence, defining characteristics and user perspectives.

Purpose: To determine the prevalence of control devices for electrically powered wheelchairs (EPWs), related characteristic features and users' views on their utility.

Method: Postal survey of users of a regional NHS wheelchair service using a purpose-designed questionnaire (n = 262, ≥18 years old).

Results: Mean age 54.

CHD5 is required for neurogenesis and has a dual role in facilitating gene expression and polycomb gene repression.

The chromatin remodeler CHD5 is expressed in neural tissue and is frequently deleted in aggressive neuroblastoma. Very little is known about the function of CHD5 in the nervous system or its mechanism of action. Here we report that depletion of Chd5 in the developing neocortex blocks neuronal differentiation and leads to an accumulation of undifferentiated progenitors.

Patient and equipment profile for wheelchair seating clinic provision.

Purpose: To characterise the provision of wheelchair seating both pre- and post-clinical intervention and compare and contrast the two largest diagnostic groups.

Method: The case notes of those attending a wheelchair seating clinic for adults over a defined period were reviewed retrospectively. A classification system was devised that delineates between the complexity and type of equipment to gain a better understanding of provision.

Clinical standards for National Health Service wheelchair and seating services in Scotland.

Purpose: To develop rigorous clinical standards for National Health Service (NHS) wheelchair and seating services in Scotland.

Method: Clinical standards and an evaluation tool were developed by a working group using a well-established methodology. The available evidence was reviewed and a person-centre, iterative, consensus decision-making approach was employed to draft the standards.

An impact assessment and critical appraisal of the ISO standard for wheelchair vocabulary.

Wheelchairs are, for users, a primary means of mobility and an important means of performing activities of daily living. A common, accepted vocabulary is required to support and foster evidence-based practice and communication amongst professionals and with users. The international standard for wheelchair vocabulary, ISO 7176-26:2007, specifies terms and definitions with the purpose of eliminating confusion from the duplication or inappropriate use of terms.

Gene-environment interplay in Drosophila melanogaster: chronic food deprivation in early life affects adult exploratory and fitness traits.

Early life adversity has known impacts on adult health and behavior, yet little is known about the gene-environment interactions (GEIs) that underlie these consequences. We used the fruit fly Drosophila melanogaster to show that chronic early nutritional adversity interacts with rover and sitter allelic variants of foraging (for) to affect adult exploratory behavior, a phenotype that is critical for foraging, and reproductive fitness. Chronic nutritional adversity during adulthood did not affect rover or sitter adult exploratory behavior; however, early nutritional adversity in the larval period increased sitter but not rover adult exploratory behavior.

Bacterial hand contamination and transfer after use of contaminated bulk-soap-refillable dispensers.

Bulk-soap-refillable dispensers are prone to extrinsic bacterial contamination, and recent studies demonstrated that approximately one in four dispensers in public restrooms are contaminated. The purpose of this study was to quantify bacterial hand contamination and transfer after use of contaminated soap under controlled laboratory and in-use conditions in a community setting. Under laboratory conditions using liquid soap experimentally contaminated with 7.

SaniTwice: a novel approach to hand hygiene for reducing bacterial contamination on hands when soap and water are unavailable.

The risk of inadequate hand hygiene in food handling settings is exacerbated when water is limited or unavailable, thereby making washing with soap and water difficult. The SaniTwice method involves application of excess alcohol-based hand sanitizer (ABHS), hand "washing" for 15 s, and thorough cleaning with paper towels while hands are still wet, followed by a standard application of ABHS. This study investigated the effectiveness of the SaniTwice methodology as an alternative to hand washing for cleaning and removal of microorganisms.

Evaluation of an electronic device for real-time measurement of alcohol-based hand rub use.

Background: Observational surveys of hand hygiene compliance are time consuming. Measuring the use of a hand hygiene product is a less time-consuming method of monitoring the frequency of hand hygiene performance.

Objective: To evaluate the usefulness of electronic devices for monitoring alcohol-based hand rub use.