Publications by authors named "Michael Hassig"

Background: Between 2006 and 2014, 10 cases of in yaks with calcium carbonate uroliths were confirmed in Switzerland, and at the same time, a sixfold calcium overhang in roughage in an affected farm was evident. The purpose of this study was the question of whether in yaks in the alpine regions of Switzerland poses a husbandry risk. The hypothesis was that elevated calcium levels in roughage led to and, thus, the formation of calcium carbonate stones.

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Chlamydia pecorum is a globally endemic livestock pathogen but prevalence data from Switzerland has so far been limited. The present longitudinal study aimed to get an insight into the C. pecorum prevalence in Swiss cattle and investigated infection dynamics.

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Objective: The aim of the present study was to describe the relationship between the biochemical variables used in metabolic profiles and various scores commonly used in herd health management of dairy cows. The Bayesian network was used to determine the relationship between metabolic blood profiles and the scores for body condition (BC), rumen fill (RF), faecal consistency (FC) and undigested fraction (UF) on a herd basis.

Materials And Methods: In each of 10 dairy herds, blood was collected from a minimum of ten lactating cows for biochemical analysis and generation of metabolic profiles.

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Objective: As dairy herds increase in size, close monitoring of health becomes a necessity, but this is expensive and labour-intensive. Early detection of febrile diseases is essential for economical and welfare reasons and to prevent the spread of disease. The goal of this study was therefore to evaluate a mobile, non-invasive technique for measuring the body temperature of cows that precludes the need for restraint of the animals.

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Objective: Claw health and carpal and tarsal lesions were assessed in a dairy herd during the transition from a tie-stall to a free-stall barn. The stress associated with the change in housing was also evaluated.

Materials And Methods: The initial size of the herd was 57 dairy cows, which were evaluated 4 times, 4-5 months apart, in a hoof-trimming chute.

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Article Synopsis
  • - The study aimed to monitor pregnancies in cows using serial transrectal sonographic exams to understand normal findings during different gestation stages, contrasting it with human medicine where such monitoring is routine. - Researchers examined 24 healthy cows to measure placentome size, uterine wall thickness, and fetal fluid characteristics over a 37-week period, finding significant correlations between placentome size and gestational age, with growth patterns revealing changes throughout the pregnancy. - The study concluded that regular sonographic assessments can provide critical insights into cow gestation, with specific metrics showing stability or notable change at various points, thereby enhancing clinical monitoring and care for pregnant cows.
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This study involved 145 cows with type-2 abomasal ulcer. The most common clinical signs were, in decreasing order of frequency, depressed demeanour (100%), partial or complete anorexia (93%), rumen atony (91%), tachycardia (90%), dark or black manure (80%), prolonged capillary refill time (71%), pale mucous membranes (69%) and tachypnoea (62%). The most common abnormal laboratory findings were azotaemia (89%), low haematocrit (82%), hypokalaemia (81%), hypoproteinaemia (74%) and metabolic acidosis (61%).

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Clostridium chauvoei is the etiologic agent of blackleg in cattle, inducing fever, severe myonecrosis, oedemic lesions and ultimately death of infected animals. The pathogen often results in such rapid death that antibiotic therapy is futile and thus vaccination is the only efficient strategy in order to control the disease. The β-barrel pore forming leucocidin Clostridium chauvoei toxin A (CctA) is one of the best characterised toxins of C.

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Bovine abortion is a worldwide problem, but despite extensive histopathologic and molecular investigations, the cause of abortion remains unclear in about 70% of cases. Cellular debris is a commonly observed histopathologic finding in the fetal placenta and is often interpreted as necrosis. In this study, the nature of this cellular debris was characterized, and histologic changes in the normal fetal placenta during pregnancy and after delivery were assessed.

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Article Synopsis
  • Cryptosporidium parvum, a key pathogen causing diarrhea in humans and animals, currently lacks effective vaccines and has limited drug options available for treatment.
  • This study utilized RNA sequencing (RNA-Seq) to analyze gene expression differences between sporozoites and intracellular stages of C. parvum, revealing 173 genes upregulated in sporozoites and 1259 in intestinal stages, along with a new calcium-dependent protein kinase identified as a potential drug target.
  • The findings highlight specific genes that are crucial for different life stages of the parasite, setting the stage for future research that may lead to new drug or vaccine development through transgenic techniques.
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Background: Drugs for the treatment of groups of pigs receiving liquid feed are frequently mixed into the feed and administered via the pipelines of the feeding installations. In-feed antimicrobials may select antimicrobial resistant strains among the bacteria which form the biofilm of these pipelines and are shed into the liquid feed.

Objective And Methods: In order to evaluate the risk of selecting antimicrobial resistant bacteria in the biofilm of liquid feeding installations, the effect of the administration of antimicrobials via the pipelines on the occurrence of antimicrobial resistance in the feed was examined in a case-control study.

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This study determined cortisol concentrations in hair that had grown for one month and in hair from a previously unshorn area and examined the effects of calendar month, pregnancy and illness on hair cortisol concentrations in dairy cows. The study was conducted over a one-year period using 27 cows. Electric clippers were used to collect two hair samples per cow each month.

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Objectives: This study examines the relationship between the morphology of the lumbosacral transitional vertebra (LTV) and asymmetrical development of the hip joints in dogs.

Methods: A total of 4000 dogs which had been consecutively scored for canine hip dysplasia were checked for the presence of a LTV. A LTV was noted in 138 dogs and classified depending on the morphology of the transverse processes and the degree of contact with the ilium.

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In pigs, Chlamydia suis has been associated with respiratory disease, diarrhea and conjunctivitis, but there is a high rate of inapparent C. suis infection found in the gastrointestinal tract of pigs. Tetracycline resistance in C.

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Chlamydial infections in pigs are associated with respiratory disease, diarrhea, conjunctivitis and other pathologies. The aim of this study was to define the prevalence of Chlamydiaceae in Swiss fattening pigs by applying sensitive and specific detection methods and to correlate prior antibiotic treatment and farm related factors with differences in prevalence. Conjunctival and fecal swabs were collected from 636 pigs in 29 Swiss fattening pig farms with and without antibiotic treatment, at the beginning and the end of the fattening period.

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Background: Eating and rumination variables were recorded in 300 healthy lactating dairy cows of 3 different breeds (100 Brown Swiss, 100 Holstein-Friesian, 100 Swiss Fleckvieh cows). Eating and rumination variables were monitored during a 24-h period using an automated system that recorded jaw movements via a pressure sensor integrated into the noseband of a halter. Phases of eating and rumination were reliably identified in the recordings based on typical patterns seen in previous studies.

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Background: This study describes the transmission of border disease virus (BDV) from a persistently infected calf to seronegative heifers in early pregnancy, resulting in persistently infected fetuses. On day 50 of pregnancy (= day 0 of the infection phase), six heifers were co-housed in a free stall with a bull calf persistently infected with BDV (pi BVD) for 60 days. The heifers underwent daily clinical examination, and blood samples were collected regularly for detection of pestiviral RNA and anti-pestivirus antibodies.

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Background: Eating and rumination variables were recorded in ten healthy cows over 5 days (group A) to generate reference intervals for comparison with the same variables recorded in ten cows in advanced pregnancy from ten days prepartum to ten days postpartum (group B). A pressure sensor integrated into the noseband of a halter recorded individual chewing movements. The endpoints calculated on a daily basis for each cow included duration of eating and rumination, number of eating and rumination phases, number of chewing cycles during eating and rumination, number of regurgitated cuds and number of chewing cycles per cud.

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Objective: To assess accuracy of noninvasive blood pressure (NIBP) measured by oscillometric device Sentinel compared to invasive blood pressure (IBP) in anaesthetized horses undergoing surgery. To assess if differences between the NIBP measured by the Sentinel and IBP are associated with recumbency, cuff placement, weight of the horse or acepromazine premedication and to describe usefulness of the Sentinel.

Study Design: Prospective study examining replicates of simultaneous NIBP and IBP measurements.

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Background: The influence of electromagnetic fields on the health of humans and animals is still an intensively discussed and scientifically investigated issue (Prakt Tierarzt 11:15-20, 2003; Umwelt Medizin Gesellschaft 17:326-332, 2004; J Toxicol Environment Health, Part B 12:572-597, 2009). We are surrounded by numerous electromagnetic fields of variable strength, coming from electronic equipment and its power cords, from high-voltage power lines and from antennas for radio, television and mobile communication. Particularly the latter cause's controversy, as everyone likes to have good mobile reception at anytime and anywhere, whereas nobody wants to have such a basestation antenna in their proximity.

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Objective: To compare post-operative pain in cats after alfaxalone or ketamine- medetomidine anaesthesia for ovariohysterectomy (OHE) and physiologic parameters during and after surgery.

Study Design: Prospective 'blinded' randomized clinical study.

Animals: Twenty-one healthy cats.

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Background: An automated technique for recording eating and rumination behaviour was evaluated in ten lactating Brown Swiss cows by comparing data obtained from a pressure sensor with data obtained via direct observation over a 24-hour period. The recording device involved a pressure sensor integrated in the noseband of a halter. The analysed variables included number and duration of individual rumination, eating and resting phases, total daily length of these phases and number of cuds chewed per day.

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Background: This retrospective study describes the clinical and laboratory findings, treatment and outcome of 461 cattle with caecal dilatation.

Results: The general condition and demeanor were abnormal in 93.1% of cases, and 32.

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Objective: To (1) determine suction tip (intermittent and continuous mode) contamination rate in orthopedic surgery in dogs and cats; (2) examine the effect of surgical time on contamination; and (3) report bacteria isolated.

Study Design: Clinical study.

Sample Population: Clean orthopedic surgeries (n = 50).

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