Subsurface tissue lesions created using an Nd:YAG laser and a sapphire contact cooling probe.

Background And Objectives: This study investigates deep laser coagulation of tissue in combination with contact cooling of the tissue surface for potential use in noninvasive procedures in urology.

Study Design/materials And Methods: A laser probe was designed and tested for simultaneous Nd:YAG laser irradiation and sapphire contact cooling of liver and skin tissue samples, ex vivo. Gross and histologic examination was used to quantify thermal lesion dimensions.