Clinical value of endometrial pinopodes detection in artificial donation cycles.

The aim of the study was to investigate the clinical value of pinopode detection in women with a history of multiple implantation failures after participation in assisted reproduction programmes. Forty-six women with primary infertility, three or more previous implantation failures in assisted reproduction programmes and indication for the use of donated oocytes underwent a mock cycle of endometrial preparation, based on a standard protocol. Endometrial samples were taken on days 6 and 8 of progesterone administration, and were examined under scanning electron microscope for detection and evaluation of pinopodes.