Utility of panendoscopy for the detection of unknown primary head and neck cancer in patients with a negative PET/CT scan.

We conducted a retrospective review of the records of 23 patients who had been diagnosed with regionally metastatic head and neck squamous cell carcinoma from an unknown primary tumor. Our goal was to assess the utility of panendoscopy in locating the primary tumor in those patients whose positron-emission tomography/computed tomography (PET/CT) findings were negative. Overall, we found that PET/CT had correctly identified the unknown primary in 12 of the 23 patients (52%); panendoscopy confirmed this finding in all 12.

Immunohistochemical analysis of aquaporins in the fetal and adult vocal fold.

Objectives: The purpose of this study is to identify and compare the presence and location of aquaporins in the fetal and adult larynx using immunohistochemical techniques.

Methods: Immunohistochemical staining was performed on adult and fetal true vocal fold specimens. The presence and location of aquaporins -1, -2 and -3 in the fetal specimens were then compared to the adult specimens.

Metastatic breast cancer to the lower eyelid.

Objectives: To present a case of metastatic breast cancer to the lower eyelid and to review the literature.regarding the epidemiology and clinical features of cutaneous metastases to the eyelid.

Methods: Case report describing a 68-year-old female with metastatic breast cancer to the lower eyelid.