Publications by authors named "Michael G. Kamykowski"
Article Synopsis
- Obstructive sleep apnoea (OSA) is linked to a higher risk of cognitive impairment and dementia, potentially involving Alzheimer's disease pathology.
- This study focused on the relationship between sleep patterns (specifically non-rapid eye movement slow-wave activity or SWA) and the accumulation of amyloid, a protein associated with Alzheimer's, in older adults with OSA.
- The results showed that increased slow oscillation (SO) activity in sleep was correlated with greater amyloid accumulation, while certain sleep patterns also indicated a potential reduction in amyloid buildup.
Disruption of the default mode network is a hallmark of Alzheimer's disease, which has not been extensively examined in atypical phenotypes. We investigated cross-sectional and 1-year longitudinal changes in default mode network sub-systems in the visual and language variants of Alzheimer's disease, in relation to age and tau. Sixty-one amyloid-positive Alzheimer's disease participants diagnosed with posterior cortical atrophy ( = 33) or logopenic progressive aphasia ( = 28) underwent structural MRI, resting-state functional MRI and [F]flortaucipir PET.
View Article and Find Full Text PDFConducted electrical weapons are designed to cause temporary electro-muscular incapacitation (EMI) without significant injury. The objective of this study was to assess the risk and cause of spinal injury due to exposure to a benchtop EMI device. Porcine subjects were exposed to 19 and 40 Hz electrical stimuli for a prolonged duration of 30 sec.
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