Publications by authors named "Michael G Mihayo"

The rapid diagnosis of coronavirus disease 2019 (COVID-19) is critical for comprehensive public health response strategies, and self-testing with antigen rapid diagnostic tests (Ag-RDTs) presents opportunities to test in hard-to-reach communities. Therefore, we evaluated the acceptability, feasibility, and uptake of Ag-RDT self-testing at the community level in Tanzania. From June to October 2022, symptomatic individuals or those with recent contact with a known or suspected COVID-19 patient were offered assisted testing and self-testing within mining communities and at transport hubs.

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Although studies on COVID-19 vaccine hesitancy are being undertaken widely worldwide, there is limited evidence in Tanzania. This study aims to assess the sociodemographic factors associated with COVID-19 vaccine hesitancy and the reasons given by unvaccinated study participants. We conducted a mixed-method cross-sectional study with two components-health facilities and communities-between March and September 2022.

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The rapid and accurate diagnosis of Plasmodium falciparum malaria infection is an essential factor in malaria control. Currently, malaria diagnosis in the field depends heavily on using rapid diagnostic tests (RDTs) many of which detect circulating parasite-derived histidine-rich protein 2 antigen (PfHRP2) in capillary blood. P.

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Background: Malaria is an important public health problem in Tanzania. The latest national malaria data suggests rebound of the disease in the country. Anopheles arabiensis, a mosquito species renowned for its resilience against existing malaria vector control measures has now outnumbered the endophagic and anthrophilic Anopheles gambiae sensu stricto as the dominant vector.

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Article Synopsis
  • This study aimed to estimate the prevalence of Plasmodium falciparum (PfPR) as part of a Phase III trial for a malaria vaccine, conducted across 8 sites in 6 African countries from 2011 to 2013.
  • The research involved about 26,611 participants, focusing on various age groups, and utilized surveys during peak malaria transmission seasons to gather medical histories and blood samples for testing.
  • Results indicated that PfPR varied significantly by region and age, showing lower prevalence in younger children in certain areas, while overall, higher prevalence was found in the 5-19 age group, with significant correlations identified between high parasitaemia and occurrences of fever and anemia.
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