Comparison of the vascularity of fasciocutaneous tissue and muscle for coverage of open tibial fractures.

Background: Early coverage with vascularized soft-tissue flaps has dramatically improved the outcome in open tibial fractures. However, the ideal tissue for covering open fractures remains controversial. Several clinical studies suggest that muscle is superior to fasciocutaneous tissue; this is attributed to the presumed higher vascularity of muscle, although experimental evidence is inconclusive.

Comparison of the healing of open tibial fractures covered with either muscle or fasciocutaneous tissue in a murine model.

The objective of this study was to compare the effects of soft tissue coverage by either muscle or fasciocutaneous tissue on the healing of open tibial fractures in a murine model. An open tibial fracture, stripped of periosteum with intramedullary fixation, was created in mice. Experimental groups were devised to allow exclusive comparison of either muscle alone or skin plus fascia in direct contact with healing bone.