Ocular and facial injuries sustained by goaltenders in the National Hockey League: a preventable problem.

Objective: Despite mandatory helmets and face masks, professional and amateur goaltenders continue to be at risk for eye and facial injuries. Better understanding of the mechanism of injury would help in optimizing goaltender equipment. The goal of this study was to identify eye and orbital injuries to goaltenders in the National Hockey League (NHL) over the past 5 seasons.

The 2016 American Academy of Ophthalmology Hydroxychloroquine Dosing Guidelines For Short, Obese Patients.

Purpose: The increasing prevalence of obesity over the past 60 years implies the need to reassess the risk of hydroxychloroquine retinopathy (HR) in obese women using the American Academy of Ophthalmology (AAO) 2016 guidelines.

Design: Cross-sectional study.

Participants: Medical records of 64 patients with HR from the practices of 2 ophthalmologists, 11 of whom were women with body mass index of 30 kg/m or more, were reviewed.

Eye and Orbital Injuries in Sports.

Sports-related eye and orbital injuries continue to occur regularly and may have serious consequences. They are completely preventable when appropriate protection is worn, particularly with polycarbonate lenses. Eye protection is available for most sports and should be worn in accordance with the standards of regional authorities.

Retinal toxicity of high-dose hydroxychloroquine in patients with chronic graft-versus-host disease.

Objective: To evaluate retinal toxicity in patients treated with high-dose hydroxychloroquine (HCQ) (Plaquenil, Sanofi Pharmaceuticals) for chronic graft-versus-host disease (GVHD).

Design: Cohort study.

Participants: Twelve patients with chronic GVHD treated with 800 mg/day HCQ between June 2005 and December 2010.

Efficient search, mapping, and optimization of multi-protein genetic systems in diverse bacteria.

Developing predictive models of multi-protein genetic systems to understand and optimize their behavior remains a combinatorial challenge, particularly when measurement throughput is limited. We developed a computational approach to build predictive models and identify optimal sequences and expression levels, while circumventing combinatorial explosion. Maximally informative genetic system variants were first designed by the RBS Library Calculator, an algorithm to design sequences for efficiently searching a multi-protein expression space across a > 10,000-fold range with tailored search parameters and well-predicted translation rates.

Getting Patients to Protect Their Eyes During Sports.

Statistics and especially photographs can prove to patients that serious eye injuries can occur during a leisurely game of racquetball and even tennis. But getting players to actually wear certified polycarbonate eye guards can be challenging. Here are a few strategies to show patients that eye protection is essential to the game.

Eye Injuries in Squash and Racquetball Players: An Update.

In brief From the summer of 1978 to May 1981 there were 154 eye injuries from squash and 91 from racquetball reported to the eye surgeons of Canada. The ball caused 90% of the most serious racquetball injuries and 67% of those in squash. Fifty-two players reported eye injuries that occurred while wearing open eye guards.