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Publications by authors named "Michael E Zampi"

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Sensitivity of depression-like behavior to glucocorticoids and antidepressants is independent of forebrain glucocorticoid receptors.
Melanie Y Vincent Rifat J Hussain Michael E Zampi Katherine Sheeran Matia B Solomon

Brain Res

August 2013

Article Synopsis
  • The study investigates the role of glucocorticoid receptors in the brain related to depression and antidepressant effects.
  • Forebrain glucocorticoid receptor deletion in a specific mouse model (FBGRKO-T29-1) did not lead to increased depression-like behavior, contrasting with previous studies using different mouse strains.
  • The findings suggest that while forebrain glucocorticoid receptors may not be necessary for antidepressant action, other glucocorticoid receptor populations in the brain could still play a significant role in depression-related effects and treatment response.
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