Publications by authors named "Michael E Danziger"
Article Synopsis
- Thermus thermophilus is a highly heat-resistant bacterium used in genetic research, especially for studying thermophiles due to its ease of genetic manipulation.
- A method is introduced for creating precise genetic changes using a counterselectable marker that makes the bacteria sensitive to a specific chemical, enabling the removal of antibiotic resistance markers.
- The study demonstrates the effectiveness of this technique by successfully making targeted mutations in key genes and identifying large deletions in its plasmid, showcasing its potential for genome engineering.
