Publications by authors named "Michael David Chan"
Article Synopsis
- Doctors usually avoid using certain types of radiation therapy for spinal issues if the problem is really close to the spinal cord (3 mm or less).
- They normally suggest surgery followed by traditional radiation treatments for serious spinal problems, especially when surgery isn't an option.
- The case mentioned shows that new methods like combining radiation therapy with immunotherapy can lead to better results, so doctors might need to change their treatment guidelines.
Gangliogliomas are rare tumors of the central nervous system that are thought to arise from a glioneuronal precursor and consist of both neuronal and glial elements. Grade III, or anaplastic ganglioglioma (AGG), most commonly affects children and young adults, generally arises in a supratentorial location, is highly epileptogenic, and often results in diffuse local and distant failure within the craniospinal axis. Pathologically, these tumors are graded by the degree of malignancy in their glial portion and radiologic diagnosis is difficult due to the wide variation in its degree of solid and cystic components, contrast uptake, and calcification patterns.
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