STELLATE MULTIFORM AMELANOTIC CHOROIDOPATHY: Clinical and Multimodal Imaging Features.

Purpose: To describe the clinical and multimodal imaging features of stellate multiform amelanotic choroidopathy (SMACH; also known as serous maculopathy due to aspecific choroidopathy).

Methods: Retrospective observational case series of eyes presenting with SMACH. Multimodal imaging including fundus photography, optical coherence tomography (OCT), OCT angiography (OCTA), and indocyanine green angiography (ICGA) was analyzed.

Maculopathy in Patients with Monoclonal Gammopathy of Undetermined Significance.

Purpose: To describe clinical findings, laboratory values, and treatment response of patients with monoclonal gammopathy of undetermined significance (MGUS) demonstrating neurosensory macular detachment.

Design: Retrospective case series.

Participants: Seven eyes of 4 patients (3 men and 1 woman; age range, 60-81 years) with neurosensory macular detachment, treatment-resistant submacular fluid, and vitelliform material.

Confirmation of Luteinizing Hormone (LH) in Living Human Vitreous and the Effect of LH Receptor Reduction on Murine Electroretinogram.

Luteinizing hormone (LH), produced in the anterior pituitary, has been detected in cadaver eyes and LH receptors (LHRs) have been identified in the retina, with the highest density in cone photoreceptors. Our aim was to confirm the presence of LH in the living, human eye as well as to examine the potential impact of a reduction in LHR signaling on visual processing. Vitreous samples were collected from 40 patients (23 diabetics, 17 non-diabetics) who were undergoing vitrectomies for various indications.

Chorioretinal Perfusion in Persistent Placoid Maculopathy.

Persistent placoid maculopathy (PPM) is a rare clinical entity that has previously been reported in the literature with a characteristic appearance on multimodal imaging, including hypofluorescence observed on fluorescein angiogram (FA) and indocyanine green angiography (ICGA). The leading mechanisms proposed for this hypofluorescence include impaired choroidal vasculature with nonperfusion of the choriocapillaris and/or blockage of choroidal fluorescence by inflammatory deposits. This report demonstrates previously unreported characteristics of chorioretinal perfusion in a case of acute onset PPM in a 58-year-old woman.

BASAL CELL NEVUS SYNDROME PRESENTING AS EPIRETINAL MEMBRANE AND MYELINATED NERVE FIBER LAYER.

Purpose: To report a case of epiretinal membrane and myelinated nerve fiber layer, which preceded the diagnosis of basal cell nevus syndrome, in a young girl.

Methods: Observational case report.

Results: A 12-year-old girl was referred for an asymptomatic epiretinal membrane.

SPONTANEOUS BILATERAL HEMORRHAGIC CHOROIDAL DETACHMENTS ASSOCIATED WITH MALIGNANT HYPERTENSION.

Purpose: To report the details of a patient with bilateral spontaneous suprachoroidal hemorrhages related to malignant hypertension.

Methods: Observational case report with review of relevant literature.

Results: A 62-year-old man with a history of hypertension was referred secondary to bilateral temporal scotomas and persistent headache for 3 days.

The effects of cataract surgery on patients with wet macular degeneration.

Purpose: To explore whether cataract surgery contributes to the progression of wet age-related macular degeneration (wet AMD).

Design: Retrospective cohort study.

Methods: Retrospective review was performed of consecutive patients with wet AMD who underwent cataract surgery at the midpoint of a 1-year study window.

Nd:YAG membranotomy for preretinal hemorrhage secondary to valsalva retinopathy.

Purpose: To report four cases of premacular hemorrhage secondary to valsalva retinopathy treated with Nd:YAG membranotomy and discuss techniques as well as the literature.

Design: Retrospective case series.

Methods: A retrospective review was conducted for four patients with vision obstructing hemorrhage secondary to valsalva retinopathy.

Stellate nonhereditary idiopathic foveomacular retinoschisis.

Purpose: To describe a new classification of stellate nonhereditary idiopathic foveomacular retinoschisis (SNIFR).

Design: Retrospective case series and literature review.

Participants: A total of 17 patients from 5 institutions.

Immunogammopathies and acquired vitelliform detachments: a report of four cases.

Purpose: To describe the nature and evolution of acquired macular detachments in patients with immunogammopathies and to propose a mechanism for their development.

Design: Retrospective observational case series.

Methods: Three patients with multiple myeloma and 1 with light chain deposition disease were diagnosed with vitelliform macular detachments based on clinical examination, fundus autofluorescence, fluorescein angiography, and optical coherence tomography.

The duration of effect of centrifuge concentrated intravitreal triamcinolone acetonide.

Purpose: To estimate the duration of activity for intravitreal triamcinolone injected with a new technique using centrifuge concentration (Centrifuge concentrated IntraVitreal Triamcinolone, C-IVT).

Methods: All injections were performed by a single surgeon (M.D.

Time required for navigated macular laser photocoagulation treatment with the Navilas.

Background: Navilas laser is a novel technology combining photocoagulation with imaging, including fluorescein angiographic (FA) images which are annotated and aligned to a live fundus view. We determine the time necessary for planning and treatment of macular edema utilizing the Navilas.

Methods: The screen recordings during treatments were retrospectively analyzed for treatment type, number of laser shots, the duration of planning (measured from the time the planning image was selected to time of marking the last planned treatment spot), and total time of laser application.

The expanded spectrum of focal choroidal excavation.

Objective: To describe the clinical and imaging findings in patients with focal choroidal excavation.

Methods: Retrospective observational case series. The medical records of 12 patients (13 eyes) with focal choroidal excavation were reviewed.

Bacterial contamination of needles used for intravitreal injections: a prospective, multicenter study.

Purpose: To determine the incidence of bacterial contamination of needles used for intravitreal injections.

Methods: Patients undergoing intravitreal injections were enrolled prospectively. No pre-injection antibiotics were administered.

Disappearance of drusen after rhegmatogenous retinal detachment.

Purpose: To describe the disappearance of drusen after rhegmatogenous retinal detachment.

Methods: Descriptive case report.

Results: A 72-year-old man with confluent subfoveal drusen developed a rhegmatogenous retinal detachment and subsequently improved in vision with disappearance of the subfoveal drusen less than 1 month after repair.

Corticosteroids for blastomycosis-induced ARDS: a report of two patients and review of the literature.

ARDS secondary to blastomycosis is associated with a high mortality rate despite appropriate antifungal therapy. Corticosteroids are of proven benefit in the treatment of severe Pneumocystis jiroveci pneumonia and are recommended for the treatment of severe pulmonary infections with Histoplasma capsulatum. However, their role in the treatment of severe pulmonary infections with Blastomyces dermatitidis has not been established.

A pilot study of intravitreal bevacizumab for the treatment of central serous chorioretinopathy (case reports).

Background: We report the use of intravitreal bevacizumab as a new option in the treatment of central serous chorioretinopathy (CSC).

Methods: Five eyes with retinal pigment epithelium (RPE) leaks secondary to CSC received intravitreal bevacizumab (2.5 mg/0.

Central serous chorioretinopathy in patients with keratoconus.

Purpose: To report the occurrence of central serous chorioretinopathy in patients with keratoconus and discuss the possible connection between these two conditions.

Methods: Observational case series.

Results: The authors identified three subjects with keratoconus and central serous chorioretinopathy.