Publications by authors named "Michael D Cockman"
Diseases of the esophagus, damage of the esophagus due to injury or congenital defects during fetal esophageal development, i.e., esophageal atresia (EA), typically require surgical intervention to restore esophageal continuity.
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- Chronic treatment with high doses of PPAR agonists can lead to left ventricular hypertrophy (LVH), but the exact mechanism and biomarkers for it are not fully understood.
- Natriuretic peptides such as NTproANP and NTproBNP were measured to explore their potential as biomarkers for LVH in rats treated with a PPARalpha/gamma dual agonist.
- The study found correlations between cardiac changes and biomarker levels, indicating that serum NTproANP could be used to predict LVH and associated hemodynamic changes.