Publications by authors named "Michael D Brothers"

Iron is a micronutrient necessary for energy metabolism and for oxygen transport and delivery. Depletion of iron stores (iron deficiency [ID]) may lead to iron deficiency anemia (IDA), which affects mood, cognitive function, and physical performance. Previous studies indicated that iron status may decline during military training.

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  • Total haemoglobin mass (Hb(mass)) can be accurately measured using a CO rebreathing method, but measurement errors can vary across different labs, possibly due to CO leaks.
  • A study implemented a standardized leak monitoring procedure with two CO detectors to assess the impact of these leaks on Hb(mass) measurements in previous test-retest studies.
  • Results showed that measurement error was lowest without any leaks (1.9%), increased with minor leaks (3.6%), and dramatically rose with major leaks (9.3%), suggesting that careful leak monitoring is crucial to ensure accurate Hb(mass) assessments.
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Although acclimatization to moderate altitude (MA) is thought to be unnecessary or to require minimal adaptation, retrospective data from the U.S. Air Force Academy (USAFA), a military college located at 2210 m, suggested otherwise.

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  • The study assessed the impact of a 6-day acclimatization at 2200 m on the physiological changes and acute mountain sickness (AMS) during a quick ascent to 4300 m.
  • Eleven male participants performed exercises and had various physiological measures taken before and after the 6-day staging.
  • Results showed that post-staging, there were significant improvements in oxygen levels and a reduction in the incidence and severity of AMS, indicating that acclimatization helps prepare the body for higher altitudes.
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Purpose: This study examined the effects of gender on graded exercise stress test (GXT) response in moderate-altitude (MA)-acclimatized cyclists during sea-level (SL) simulation. It was hypothesized that alterations in arterial saturation would relate to changes in VO2peak.

Methods: Twenty competitive cyclists (12 males, 8 females) who were residents of MA locations underwent two randomized bicycle GXTs: one under local normoxic hypobaria, and the other under simulated SL conditions.

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While high altitude adaptations have been studied extensively, limited research has examined moderate altitude (MA: 1500 to 3000 m) adaptations and their time course, despite the fact that millions of people sojourn to or reside at MA. We retrospectively examined long-term MA acclimatization by analyzing recurring physical fitness test results and hematological data among 2147 college-age male cadets previously residing at either sea level (SL) or MA and currently attending the U.S.

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