Publications by authors named "Michael C Cantrell"
Background: Standard of care for locally advanced esophageal cancer is neoadjuvant therapy followed by surgical resection. The objective of this study is to explore perioperative factors associated with recurrence and survival among patients with locally advanced esophageal cancer.
Methods: A retrospective analysis of prospectively collected data on all consecutive minimally invasive Ivor Lewis esophagectomy cases for esophageal cancer performed from September 2013 to September 2023 was performed.
Article Synopsis
- This study aimed to identify risk factors for anastomotic leak (AL) after minimally invasive esophagectomy (MIE) and evaluate its impact on cancer recurrence and survival.
- A total of 251 patients were analyzed, revealing that 6% experienced AL, with factors like anemia and hospital complications significantly differing between those with and without AL.
- Despite these associations, AL did not significantly affect 30- or 90-day mortality rates, cancer recurrence, or overall survival, indicating that while AL is influenced by certain factors, it does not worsen long-term outcomes.
Background: Pancreatic surgery is associated with a significant risk for acute kidney injury (AKI) and clinically relevant postoperative pancreatic fistula (CR-POPF). This investigation evaluated the impact of intraoperative volume administration, vasopressor therapy, and blood pressure management on the primary outcome of AKI and the secondary outcome of a CR-POPF after pancreatic surgery.
Methods: This retrospective single-center cohort investigated 200 consecutive pancreatic surgeries (January 2018-December 2021).