Publications by Michael Brandtner

Publications by authors named "Michael Brandtner"

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Open-label simultaneous radio-chemotherapy of glioblastoma multiforme with topotecan in adults.

Markus W Gross Riglef Altscher Michael Brandtner Harald Haeusser-Mischlich Ion C Chiricuta

Clin Neurol Neurosurg

April 2005

Background: Due to its radioresistance, the prognosis of glioblastoma multiforme (GBM) remains poor. Therefore, we investigated the impact of simultaneous radio-chemotherapy with topotecan (Hycamtin) on clinical outcome, tolerability and quality of life.

Patients And Methods: In this multicenter trial, 60 patients (19 females, 41 males) with histologically proven (5x biopsy, 31x subtotal resection, 24x total resection) GBM were included.

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