Publications by authors named "Michael B West"

Article Synopsis
  • Defibrillation leads are crucial for implantable cardioverter-defibrillators (ICDs), and the LEADR trial tested the new OmniaSecure lead, showing strong safety, efficacy, and zero fractures over about 13 months.
  • The study aimed to project the long-term, 10-year fracture-free survival of the OmniaSecure lead using advanced reliability modeling and in-vivo imaging techniques.
  • Results indicated a 98.2% projected fracture-free survival rate over 10 years for the OmniaSecure lead, especially beneficial for adolescents, surpassing the performance of existing leads.
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Article Synopsis
  • The OmniaSecure defibrillation lead is a new, small-diameter lead aimed at improving targeted placement for better long-term performance in implantable cardioverter-defibrillators.
  • The LEADR pivotal clinical trial involved 643 patients and showed that the lead was successfully placed in the correct position for 99.5% of participants, with a 97.5% success rate for defibrillation at implantation.
  • The trial results indicated high safety and efficacy, with a 97.1% freedom from major complications and no lead fractures over an average follow-up of 12.7 months.
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A 91-year-old woman presented to the emergency department by ambulance after her family found her minimally responsive. Telemetry monitoring demonstrated episodes of non-sustained polymorphic ventricular tachycardia (PMVT) associated with significantly prolonged repolarization. Her medical history revealed that she was taking quinine or a derivative in three different forms: hydroxychloroquine, quinine sulfate (for leg cramps), and her gin mixed with tonic water (containing quinine).

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This case report describes the rare phenomenon of malignant conversion of benign right ventricular outflow tract ventricular tachycardia into idiopathic ventricular fibrillation 18 years after successful ablation, in the absence of any type of heart disease. We review the current literature looking at predictors for this event, with the conclusion that there are no reliable risk predictors available. Until clear guidelines exist, we suggest patients be informed and monitored for the possibility of "malignant conversion" following ablation for benign idiopathic outflow tract ventricular tachycardia.

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Vagal nerve stimulation (VNS) is widely accepted as an effective and safe therapy for refractory seizure disorders. Significant cardiac complications, such as complete heart block or symptomatic bradycardia, are extremely rare. We present a case report of a 40-year-old man with drug-resistant epilepsy, treated with VNS, who developed the late-onset (12 months after implant), stimulation-related, symptomatic advanced heart block that was initially misinterpreted for a new type of seizure.

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The crista terminalis is a fibromuscular ridge formed by the junction of the sinus venosus and primitive right atrium. In these case reports, transthoracic echocardiography suggested the presence of a right atrial mass. However, subsequent transesophageal echocardiography revealed that the "right atrial mass" was actually a prominent crista terminalis.

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