Publications by authors named "Michael Airo"
The dynamic between pulmonary hypertension (PH) and COVID-19 has been under investigation since 2020, early in the pandemic. Although the pathophysiology of PH has been well-studied, new discoveries regarding the multisystemic effects of COVID-19 are still being uncovered. The cardiopulmonary effects of COVID-19 have led investigators to inquire about the interplay between these 2 conditions.
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- Resistant hypertension (RH) is a condition where blood pressure remains high despite receiving the best medical treatment, affecting about 16% of hypertension cases.
- RH leads to more serious health issues compared to regular hypertension and indicates an underlying problem that might involve the hormone endothelin, which causes blood vessels to constrict.
- Although there are medications to block endothelin for other conditions, Aprocitentan is a new drug specifically being developed for RH, showing promising results in lowering blood pressure effectively.
A reciprocal relationship between obesity and obstructive sleep apnea (OSA) likely exists, wherein obesity contributes to OSA, and OSA-related sleep disturbances promote weight gain. It remains unclear whether continuous positive airway pressure (CPAP) affects body composition. We conducted an open-label, parallel-arm, non-randomized, matched before-after study in individuals with OSA who were starting CPAP use ( = 12) and who were not ( = 12) to examine the effects of CPAP on total body composition (via air displacement plethysmography) including fat and fat-free mass.
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