Publications by authors named "Michael A Wang"
Exp Hematol
November 2024
Article Synopsis
- Patients with sickle cell disease (SCD) experience variable pain, making management difficult; this study focuses on the role of the 5-HT1A receptor gene (HTR1A) in pain variability.
- Researchers genotyped four HTR1A variants in 131 African American SCD patients and found three variants significantly associated with acute crisis pain, with effects differing between males and females.
- The study highlights that specific genetic variants can influence pain experiences in SCD, emphasizing the need for sex-based considerations in pain management strategies.
