Ruthenium, copper and ruthenium-copper complexes of an unsymmetrical phosphino pyridyl 1,8-naphthyridine PNNN ligand.

A new unsymmetrical dinucleating phosphino pyridyl 1,8-naphthyridine ligand PNNN is reported. Reaction with CuCl gave the dicopper complex [Cu(μ-Cl)(PNNN)] (1). In contrast, complexation of [RuCl(cymene)] yielded a monometallic species [RuCl(cymene)(PNNN)]Cl ([2]Cl) in which the Ru is bound to the κ-N,N, rather than κ-P,N, binding pocket.

A one-pot reduction route to bimetallic manganese 1,8-naphthyridine complexes.

Reaction of the dinucleating ligand 2,7-bis(6-methyl-2-pyridyl)-1,8-naphthyridine (L) with the Mn and Mn precursors MnBr(CO) and MnCl resulted in the formation of the monometallic complexes [MnBr(CO)(L)] (1) and [MnCl(L)] (3). In both cases, formation of bimetallic manganese complexes could be achieved by reduction with KC, yielding the carbonyl-bridged complex [Mn(CO)(L)] (2) and the helicate complex [Mn(L)] (4), respectively. EPR results demonstrate that 4 represents a novel, weakly antiferromagnetically coupled homovalent dimer ( = -0.

Copper and Zinc Complexes of 2,7-Bis(6-methyl-2-pyridyl)-1,8-naphthyridine─A Redox-Active, Dinucleating Bis(bipyridine) Ligand.

The ligand 2,7-bis(6-methyl-2-pyridyl)-1,8-naphthyridine () acts as a dinucleating analogue of ubiquitous 2,2'-bipyridine ligands. Coordination of to [Cu(NCMe)]PF and Zn(OAc) led to isolation of monometallic [Zn(OAc)()], homobimetallic [Cu()][PF], and heterobimetallic [CuZn(μ-OAc)()]PF complexes. The redox-active nature of the ligand enables access to four redox states of the complex [Cu()][PF].

Cooperative approaches in catalytic hydrogenation and dehydrogenation.

Metal-ligand cooperativity (MLC) is an established strategy for developing effective hydrogenation and dehydrogenation catalysts. Metal-metal cooperativity (MMC) in bimetallic complexes is not as well understood, and to date has had limited implementation in (de)hydrogenation. Herein we use (de)hydrogenation processes as a platform to examine modes of cooperativity, with a particular focus on catalytic mechanisms.

Influences of unconscious priming on voluntary actions: Role of the rostral cingulate zone.

The ability to make voluntary, free choices is fundamental to what it means to be human. A key brain region that is involved in free choices is the rostral cingulate zone (RCZ), which is part of the medial frontal cortex. Previous research has shown that activity in this brain region can be modulated by bottom-up information while making free choices.

The histone chaperone Vps75 forms multiple oligomeric assemblies capable of mediating exchange between histone H3-H4 tetramers and Asf1-H3-H4 complexes.

Vps75 is a histone chaperone that has been historically characterized as homodimer by X-ray crystallography. In this study, we present a crystal structure containing two related tetrameric forms of Vps75 within the crystal lattice. We show Vps75 associates with histones in multiple oligomers.

Health care professionals' reactions to patient pain: impact of knowledge about medical evidence and psychosocial influences.

Unlabelled: This study examined the impact of evidence concerning the presence of 1) a biomedical basis for pain and 2) psychosocial influences on practitioner appraisals of patient pain experiences. Furthermore, the potential moderating role of patient pain behavior was examined. In an online study, 52 general practitioners and 46 physiotherapists viewed video sequences of 4 patients manifesting pain, with accompanying vignettes describing presence or absence of medical evidence and psychosocial influences.

Interhemispheric communication influences reading behavior.

We can read words at an amazing speed, with the left hemisphere taking the burden of the processing in most readers (i.e., over 95% of right-handers and about 75% of left-handers).

Theta burst stimulation dissociates attention and action updating in human inferior frontal cortex.

Everyday circumstances require efficient updating of behavior. Brain systems in the right inferior frontal cortex have been identified as critical for some aspects of behavioral updating, such as stopping actions. However, the precise role of these neural systems is controversial.

STOP-IT: Windows executable software for the stop-signal paradigm.

The stop-signal paradigm is a useful tool for the investigation of response inhibition. In this paradigm, subjects are instructed to respond as fast as possible to a stimulus unless a stop signal is presented after a variable delay. However, programming the stop-signal task is typically considered to be difficult.