Publications by authors named "Michael A Ojo"
Article Synopsis
- TLRs (Toll-like receptors) start immune responses by using TIR (Toll/IL-1R) domains, but some bacteria have their own TIR proteins to evade immune detection.
- Initial studies on a bacterial TIR from Acinetobacter baumannii revealed structural insights but didn't clarify how it binds NAD, leading to further investigation.
- A collaborative research project involving undergraduates aimed to identify key amino acids for the NADase activity of TIR domains from A. baumannii and E. coli, providing new insights into their function and reaffirming the effectiveness of student-led research experiences.
Objective: The aim of this study is to compare the proliferative capacity and antiapoptotic capacity of unicystic ameloblastoma (UA), odontogenic keratocyst (OKC), dentigerous cyst (DC) and radicular cyst (RC) by assessing the Ki-67 labeling index (LI) and Bcl-2 LI, respectively.
Materials And Methods: Formalin-fixed, paraffin-embedded tissue blocks of twenty-three histopathologically diagnosed UAs, 6 OKCs, 8 DCs and 10 RCs were selected from the archival specimens. Five micrometer thick sections of tissue blocks of the lesions were processed for immunohistochemical staining with Ki-67 and Bcl-2.
Objective: This study aims to determine the clinical features which are helpful as significant indicators in the diagnosis of malignant and nonmalignant nonodontogenic orofacial tumors.
Materials And Methods: This was a prospective study performed on patients with swellings in the oral and maxillofacial region clinically suspicious of being tumors of nonodontogenic origin in a Nigerian Tertiary Health Institution. The statistical variables that were analyzed included patients' resume, clinical and radiological features as well as the histopathological diagnosis of the lesions.
Aim: The aim of this study was to identify the causes and patterns of tooth loss among Nigerian adults.
Background: Tooth loss continues to be a major problem in clinical dentistry and has received significant attention in everyday dental practice. In Nigeria there is a discernible lack of current data that would explain the reasons and patterns of tooth loss from its different geopolitical zones.
Purpose: We aimed to determine the contributory percentage of histopathologic diagnoses of routine biopsies and to ascertain the possible indicators for histopathologic examination to confirm the clinical diagnosis of periradicular lesions of extracted teeth.
Patients And Methods: This was a prospective study carried out over a period of 8 months on patients who had single tooth extraction and routine histopathologic examination of recoverable periradicular tissues from extracted teeth.
Results: A total of 136 patients participated in this study.