Mathematical modeling to understand the role of bivalent thrombin-fibrin binding during polymerization.

Thrombin is an enzyme produced during blood coagulation that is crucial to the formation of a stable clot. Thrombin cleaves soluble fibrinogen into fibrin, which polymerizes and forms an insoluble, stabilizing gel around the growing clot. A small fraction of circulating fibrinogen is the variant γA/γ', which has been associated with high-affinity thrombin binding and implicated as a risk factor for myocardial infarctions, deep vein thrombosis, and coronary artery disease.

Fat-Free Mass and the Balance Error Scoring System Predict an Appropriate Maximal Load in the Unilateral Farmer's Walk.

This study quantified and compared unilateral farmer's walk (UFW) performance in recreationally active males and females, and determined if additional variables allowed for the prediction of a maximal safe load. Anthropometric (height, body weight (BW), body mass index, body fat percentage, fat-free mass (FFM), and fat mass), muscular endurance (maximal duration side bridge), and balance (Balance Error Scoring System (BESS)) tests were completed. Participants performed a series of 20 s UFW trials (non-dominant side) at a cadence of 66 beats/min.