Interactions of decapentaplegic, wingless, and Distal-less in the Drosophila leg.

The genes decapentaplegic, wingless, and Distalless appear to be instrumental in constructing the anatomy of the adult Drosophila leg. In order to investigate how these genes function and whether they act coordinately, we analyzed the leg phenotypes of the single mutants and their inter se double mutant compounds. In decapentaplegic the tarsi frequently exhibit dorsal deficiencies which suggest that the focus of gene action may reside dorsally rather than distally.