Child Maltreatment Prevention Service Cases are Significantly Reduced During the COVID-19 Pandemic: A Longitudinal Investigation Into Unintended Consequences of Quarantine.

Unprecedented financial and emotional stress, paired with measures to slow the spread of COVID-19 (e.g., school closures), place youth at risk for experiencing increased rates of abuse.

Antibody-conjugated paramagnetic nanobeads: kinetics of bead-cell binding.

Specific labelling of target cell surfaces using antibody-conjugated paramagnetic nanobeads is essential for efficient magnetic cell separation. However, studies examining parameters determining the kinetics of bead-cell binding are scarce. The present study determines the binding rates for specific and unspecific binding of 150 nm paramagnetic nanobeads to highly purified target and non-target cells.

Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects.

Background: Atopic dermatitis (AD) is a major inflammatory condition of the skin caused by inherited skin barrier deficiency, with mutations in the filaggrin gene predisposing to development of AD. Support for barrier deficiency initiating AD came from flaky tail mice, which have a frameshift mutation in Flg and also carry an unknown gene, matted, causing a matted hair phenotype.

Objective: We sought to identify the matted mutant gene in mice and further define whether mutations in the human gene were associated with AD.

Spiral wave dynamics under feedback via an equilateral triangular sensory domain.

We perform a numerical study of the trajectories of spiral wave cores in excitable systems whose excitability is modulated in proportion to the integral of the activity in a sensory domain in the shape of an equilateral triangle. As a result of this domain shape having vertices opposite sides, unusual forms of lobed limit cycles occur, which are destroyed and then re-form as the domain size is varied. Some key results are also demonstrated experimentally using the light-sensitive Belousov-Zhabotinsky reaction.