An analysis of the evidence underpinning the national comprehensive cancer network practice guidelines.

Objective: This study assesses the quality and completeness of systematic reviews (SRs) included by the National Comprehensive Cancer Network (NCCN) cancer screening clinical practice guidelines (CPGs).

Methods: We evaluated SRs according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) and AMSTAR-2 (A Measurement Tool to Assess systematic Reviews).

Results: Seven NCCN CPGs were included with 109 SRs.