Publications by authors named "Mica Fujita"
Background: Food-derived nucleic acids exhibit various biological activities and may act as nutrients. Oral ingestion of the nucleic acid fraction (NAF) of salmon milt extract hydrolysates enhances cognitive function in mice although their active ingredients have not yet been identified, and detailed mechanisms of action are unknown.
Objective: To identify active ingredients enhancing cognitive function contained in the NAF and its possible underlying mechanism.
The nucleic acids found in food play a crucial role in maintaining various bodily functions. This study investigated the potential anticancer effects of dietary nucleic acids, an area that is still not fully understood. By utilizing an in vivo mouse model and an in vitro cell model, we discovered an anti-proliferative impact of RNA in both systems.
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- The study investigates the effects of dietary DNA from salmon on stress relief in male mice under emergency conditions.
- Mice fed a diet with 1% DNA-Na showed reduced stress levels, unlike those fed yeast-derived RNA.
- Additionally, older mice experienced increased brain inflammation, but those given DNA-Na had suppressed inflammation markers, indicating potential benefits of dietary DNA for managing stress-related brain issues in aging.