Publications by authors named "Miaozhu Yin"

The serum ceruloplasmin assay is the most commonly used test for diagnosing Wilson's disease (WD). Despite the utility of non-invasive tests for diagnosing WD, no such tests have been developed. Therefore, we aimed to identify a safe and non-invasive assay and determine the factors associated with salivary ceruloplasmin.

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Article Synopsis
  • Hepatolenticular degeneration (HLD) is a genetic disease that affects how the body handles copper, causing problems in different organs, especially in female reproductive health.
  • In a study, researchers tested a substance called berberine on mice with HLD to see if it could help protect their ovaries from damage.
  • The results showed that berberine improved the health of the ovaries by reducing harmful processes and stress caused by excess copper, leading to better ovulation and healthier ovary structure.
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Copper is a toxic heavy metal that causes various damage when it accumulates in the body beyond the physiological threshold. Wilson disease (WD) is an inherited disorder characterized by impaired copper metabolism. Reproductive damage in male patients with WD is gradually attracting attention.

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