Research on Constitutive Modeling of DH460 Continuous Casting Steel with the Solidification End Reduction Process.

The constitutive model was commonly used to describe the flow stress of materials under specific strain, strain rate, and temperature conditions. In order to study the thermal-mechanical behavior of DH460 continuous casting steel during the solidification end heavy reduction (HR) process accurately. The high-temperature compression experiment was carried out, and phenomenological constitutive models were established based on the experimental results.

Donor-derived stem cell infusion for sustained pancytopenia after CD19 CAR-T therapy for relapsed patients post allogeneic stem cell transplantation.

Objectives: To investigate the effectiveness of donor-derived chimeric antigen receptor T (CAR-T) cells in the treatment of relapsed cases after allogeneic hematopoietic stem cell transplantation (allo-HSCT), and whether donor-derived peripheral blood stem cells (PBSCs) have a therapeutic effect on pancytopenia after CAR-T cell therapy.

Methods: We analyzed data from five adults with B-cell acute lymphoblastic leukemia (ALL) who had relapse after allo-HSCT and received donor-derived CAR-T cell therapy and donor-derived PBSCs to promote hematopoietic recovery.

Results: All patients had negative minimal residual disease after CAR-T therapy, grade 1-2 cytokine release syndrome, and developed grade 4 hematologic toxicity.

A new study on the growth behavior of austenite grains during heating processes.

In this paper, the effects of the heating temperature and holding time on the austenite grain growth of SCM435 steel were studied and analyzed in terms of the average, macro-axis and minor-axis size of the grains. The results indicated that the classical Sellars model was highly consistent for describing the growth stage of the new austenite but poorly described the initial nucleation-growth stage and stability stage of the austenite. A new model that expresses the average austenite grain growth of SCM435 steel was developed, and the values calculated based on this model were highly consistent with the actual measured values.

Tens of micron-sized unilamellar nanosheets of Y/Eu layered rare-earth hydroxide: efficient exfoliation via fast anion exchange and their self-assembly into oriented oxide film with enhanced photoluminescence.

Layered rare-earth hydroxide (LRH) crystals of (YEu)(OH)NO·HO with a lateral size of ∼ 300 m and a thickness of ∼ 9 m have been synthesized via a hydrothermal reaction of mixed nitrate solutions in the presence of mineralizer NHNO at 200 °C for 24 h. LRH exhibits the ability to undergo intercalation and anion exchange with DS (CHOSO) via hydrothermal treatment. Compared with traditional anion exchange at room temperature, hydrothermal processing not only shortens the anion exchange time from 720 to 24 h but also increases the basal spacing.

[Hereditary hemorrhagic telangiectasia resulted from a nonsense mutation Arg479 Stop in the ALK-1 gene].

Objective: To identify the gene mutations in a pedigree with hereditary hemorrhagic telangiectasia.

Methods: Genomic DNA was extracted from the peripheral blood of the propositus. All of the exons, intron/exon boundaries and the 5' untranslation regions (UTR) of the ALK-1 and endoglin gene were amplified by polymerase chain reaction (PCR).