Publications by authors named "Miaoru Liu"
J Control Release
January 2025
Article Synopsis
- - Severe acute pancreatitis (SAP) is a serious inflammatory condition of the pancreas with limited treatment options, prompting the development of a new nanotherapeutic called pHA@IBNCs to alleviate inflammation and restore intestinal health.
- - The pHA@IBNCs are formed by combining an antioxidant (EGCG), an anti-inflammatory cytokine (IL-22), and a framework protein (bovine serum albumin), then coated with a modified hyaluronic acid to target damaged cells in the pancreas and intestines.
- - When administered, the pHA@IBNCs effectively accumulate at inflammation sites, releasing their therapeutic agents in response to the high levels of reactive oxygen species (ROS) present, which helps reduce inflammation and
