Publications by authors named "Miaomiao Ning"
Metabolomic Profiling Reveals That Exercise Lowers Biomarkers of Cardiac Dysfunction in Rats with Type 2 Diabetes.
Antioxidants (Basel)
September 2024
Article Synopsis
- * A study using metabolomics on rats with T2DM found that while diabetes disrupted 1029 myocardial metabolites, aerobic exercise restored 208 of these, indicating potential therapeutic effects.
- * Ten metabolic biomarkers, such as xanthine and l-arginine, were identified as significant in improving heart function and may play a crucial role in mitigating cardiac issues related to diabetes through aerobic exercise.
Acute aerobic exercise regulation of myocardial calcium homeostasis involves CASQ1, CASQ2, and TRDN.
J Appl Physiol (1985)
October 2023
Exercise maintains cardiac calcium homeostasis and promotes cardiovascular health. This study explored temporal changes of calcium-related myocardial transcriptome changes during the recovery phase following a single bout of moderate-intensity aerobic exercise. Healthy male Sprague-Dawley rats were anesthetized with sodium pentobarbital after moderate-intensity aerobic exercise at four time points (0, 12, 24, and 72 h postexercise).
View Article and Find Full Text PDFUnlabelled: Macrophage carriage, release, and antitumor activities of polymeric nanoformulated paclitaxel (PTX) were developed as a novel delivery system for malignant glioma. To achieve this goal, the authors synthesized PTX-loaded nanoformulations (nano-PTX), then investigated their uptake, release, and toxicological properties. Chemosensitivity was significant in U87 cells (P < 0.
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