LncRNA PVT1 promotes malignant progression by regulating the miR-7-5p/CDKL1 axis in oral squamous cell carcinoma.

Oral squamous cell carcinoma (OSCC), one of the most common types of head and neck squamous cell carcinoma (HNSCC), is characterized by high incidence and mortality. PVT1 is a long non-coding RNA (lncRNA) that plays an oncogenic role in various cancer types. This study aims to reveal the role and underlying molecular mechanism of PVT1 in OSCC progression.

Digital PCR-based methylation testing in acute myeloid leukemia: diagnosis, prognosis and monitoring.

Acute myeloid leukemia (AML) is a challenging disease with high rates of recurrence. The role of the cancer-related gene in AML has not been widely studied. Peripheral blood samples were collected from 73 AML patients and 68 healthy controls.