Efficacy of Thermus thermophilus Fermentation Extract in Promoting Hair Growth and Improving Scalp Health in Androgenic Alopecia: A Clinical and In Vitro Study.

Background: Androgenic alopecia (AGA) is a widespread form of hair loss characterized by the gradual reduction in follicular size and reduced hair density, with unsatisfactory treatments.

Aims: This study explores the therapeutic potential of a novel fermented extract, Thermus thermophilus fermentation extract (TTFE), in mitigating the effects of AGA.

Methods: The research integrates in vitro assays utilizing various hair-growth-related cells with a 12-week clinical trial involving 32 male subjects diagnosed with AGA.

Ellagitannins From Pomegranate Flower With Whitening and Anti-Skin Photoaging Effect.

A new depside glucoside rosarugoside E (1), together with four known compounds punicalagin (2), corilagin (3), granatin B (4), and ellagic acid (5) were isolated from the ethanol extract of pomegranate (Punica granatum L.) flower. Their structures were identified based on careful analysis of various spectral data including ultraviolet, infrared, high-resolution electrospray ionization-mass spectrometry, and 1D and 2D nuclear magnetic resonance.