Publications by authors named "Miaojie Yang"

Article Synopsis
  • - Centella asiatica is a medicinal plant known for its high content of triterpenoids, commonly used in Asia to treat skin issues like acne.
  • - Researchers isolated 21 triterpenoid compounds from the plant, analyzing their structures through NMR and HRESIMS, including unique compounds with rare aldehyde groups.
  • - In vitro tests showed that 20 of these compounds effectively enhanced cell survival and reduced damage from UVB exposure, suggesting they may serve as natural protectants against skin aging.
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Hypoxia and high concentration of glutathione (GSH) in tumor seriously hinder the role of reactive oxygen species (ROS) and oxygen-dependence strategy in tumor treatment. In this work, a self-generating oxygen and self-consuming GSH hyaluronic acid (HA)-coated porphyrin nanoplatform (TAPPP@CaO/Pt(IV)/HA) is established for enhancing photodynamic/ion/chemo targeting synergistic therapy of tumor. During the efforts of ROS production by nanosystems, a GSH consuming strategy is implemented for augmenting ROS-induced oxidative damage for synergetic cancer therapy.

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