Publications by authors named "Miao-zi Gong"
Article Synopsis
- A rare case of bladder tumor in a 61-year-old female with spina bifida and neurogenic bladder, initially presenting as an unexplained "well-filled" bladder.
- A cystoscopy revealed a large mass, initially mistaken for an infectious necrotic mass, which later showed signs of transitional cell carcinoma.
- The case highlights the need for regular screenings in spina bifida patients to detect atypical bladder tumors early for better treatment outcomes.
Fungus ball and fungal emphysematous cystitis are two rare complications of fungal urinary tract infection. A 53-year-old male patient presented with these complications caused by Candida tropicalis simultaneously. The predisposing factors were diabetes mellitus and usage of broad-spectrum antibiotics.
View Article and Find Full Text PDF[Identification of nucleolar localization signal sequence of tumor metastasis suppressor gene-1].
Zhonghua Bing Li Xue Za Zhi
November 2011
Objective: To identify the putative specific localization signal sequence of tumor metastasis suppressor gene-1 (TMSG-1) and to explore the mechanism of subcellular localization of TMSG-1 protein.
Methods: Vectors expressing green fluorescence protein (GFP) tagged different TMSG-1 fragments were generated and transfected into human embryo kidney 293 (HEK293) cells. The expression of those fusion proteins was detected by Western blotting and their subcellular localizations were observed by laser confocal microscope.
[Transcriptional activation of TMSG-1 by complex of KLF6 and Sp1].
Zhonghua Bing Li Xue Za Zhi
August 2011
Objective: To investigate the regulatory mechanism of the transcription of tumor metastasis suppressor gene TMSG-1.
Methods: Luciferase reporter assay and site-directed mutagenesis were used to analyze the regulatory region of TMSG-1. Electrophoretic mobility shift assay (EMSA) and chromatin immunoprecipitation (ChIP) were carried out to verify the interaction of KLF6 and Sp1 with the regulatory region of TMSG-1.