Publications by authors named "Miao Xiang"

Fluctuating Asymmetry (FA) in fish otoliths is an indicator of arbitrarily tiny variations between bilateral otolith characters, and it serves as an effective indicator of growth and developmental differences due to environmental conditions. Due to their unique resident traits, the Coilia brachygnathus can provide a potential insight to the environmental pressure reflected by its otolith FA. In this study, 228 C.

View Article and Find Full Text PDF

Electrosynthesis of multicarbon products, such as CH, from CO reduction on copper (Cu) catalysts holds promise for achieving carbon neutrality. However, maintaining a steady high current-level CH electrosynthesis still encounters challenges, arising from unstable alkalinity and carbonate precipitation caused by undesired ion migration at the cathode under a repulsive electric field. To address these issues, we propose a universal "charge release" concept by incorporating tiny amounts of an oppositely charged anionic ionomer (e.

View Article and Find Full Text PDF

() infection is the primary risk factor for the progress of gastric diseases. The persistent stomach colonization of is closely associated with the development of gastritis and malignancies. Although the involvement of progranulin (PGRN) in various cancer types has been well-documented, its functional role and underlying mechanisms in gastric cancer (GC) associated with infection remain largely unknown.

View Article and Find Full Text PDF

Lithium-sulfur (Li-S) batteries offer high theoretical capacity but are hindered by poor rate capability and cycling stability due to sluggish LiS precipitation kinetics. Here a sulfonate-group-rich liquid crystal polymer (poly-2,2'-disulfonyl-4,4'-benzidine terephthalamide, PBDT) is designed and fabricated to accelerate LiS precipitation by promoting the desolvation of Li from electrolyte. PBDT-modified separators are employed to assemble Li-S batteries, which deliver a remarkable rate capacity (761 mAh g at 4 C) and cycling stability (500 cycles with an average decay rate of 0.

View Article and Find Full Text PDF

Background: Non-small cell lung cancer (NSCLC) is the leading cause of morality among all malignant tumors. Smoking is one of the most important causes of NSCLC, which contributes not only to the initiation of NSCLC but also to its progression. The identification of specific biomarkers associated with smoking will promote diagnosis and treatment.

View Article and Find Full Text PDF

Co-Mo-S based catalysts have promising applications in both the hydrogen evolution reaction (HER) and hydrodesulfurization (HDS). Herein, Co-Mo-S catalyst and Co-Mo-S catalyst with and without NaBH modification have been successfully synthesized by a simple hydrothermal synthesis method. Co-Mo-S catalysts with NaBH modification show better catalytic activity towards both HDS and the HER.

View Article and Find Full Text PDF

The highly expressed oncogenic factor Krüppel-like factor 5 (KLF5) promotes various cancerous processes, such as cell growth, survival, anti-apoptosis, migration and metastasis, particularly in lung cancer. Nevertheless, the modifications to KLF5 after translation are poorly understood. Protein arginine methyltransferase 5 (PRMT5) is considered as an oncogene known to be involved in different types of carcinomas, including lung cancer.

View Article and Find Full Text PDF

Background: Papillary thyroid cancer (PTC) is the most common type of differentiated thyroid cancer. Early identification of patients at higher risk of recurrence may allow to improve relevant follow-up strategies and plan tailored treatment. Inflammation play an important role in the prognosis of cancer.

View Article and Find Full Text PDF

Background: Anastomotic stricture is a common underlying cause of long-term morbidity after hepaticojejunostomy (HJ) for bile duct injury (BDI) following cholecystectomy. However, there are no methods for predicting stricture risk. This study was aimed at establishing two online calculators for predicting anastomotic stricture occurrence (ASO) and stricture-free survival (SFS) in this patient population.

View Article and Find Full Text PDF

Immune checkpoint blockade (ICB) therapy targeting PD-1/PD-L1 has shown durable clinical benefits in lung cancer. However, many patients respond poorly to ICB treatment, underscoring an incomplete understanding of PD-L1 regulation and therapy resistance. Here, we find that MTSS1 is downregulated in lung adenocarcinoma, leading to PD-L1 upregulation, impairment of CD8 lymphocyte function, and enhanced tumor progression.

View Article and Find Full Text PDF
Article Synopsis
  • Researchers have developed stable single-atomic catalysts made by creating atomic bonds between platinum (Pt) and iron (Fe), which enhances the catalytic performance significantly.
  • These catalysts are supported by defective iron oxide nanosheets on reduced graphene oxide, leading to high activity, stability, and selectivity for diboration reactions.
  • Experimental findings indicate that fast electron transfer from Fe to Pt in these catalysts helps stabilize the single-atom Pt sites and boosts their catalytic efficiency.
View Article and Find Full Text PDF
Article Synopsis
  • Radical gastrectomy can lead to various complications, but acute appendicitis shortly after the surgery is uncommon and may be mistaken for duodenal stump leakage.
  • A 77-year-old woman experienced lower right abdominal pain 14 days post-surgery, with elevated inflammatory markers and imaging showing fluid and swelling around the appendix.
  • The patient underwent laparoscopic appendectomy, was diagnosed with acute purulent appendicitis, and successfully continued her chemotherapy after recovery.
View Article and Find Full Text PDF

Chronic inflammation and an immunosuppressive microenvironment promote prostate cancer (PCa) progression and diminish the response to immune checkpoint blockade (ICB) therapies. However, it remains unclear how and to what extent these two events are coordinated. Here, we show that ARID1A, a subunit of the SWI/SNF chromatin remodeling complex, functions downstream of inflammation-induced IKKβ activation to shape the immunosuppressive tumor microenvironment (TME).

View Article and Find Full Text PDF

Background: We investigated differentially methylated and expressed genes between panic disorder (PD) and healthy controls (HCs) to determine whether DNA methylation and expression level of candidate genes can be used as biomarkers for diagnosis and early response.

Methods: Illumina infiniun Methylation EPIC (850 k) Beadchip for genome-wide methylation screening and mRNA sequencing was conducted in a discovery set (30 patients with PD and 30 matched HCs). The candidate gene loci methylation and expression were verified in an independent validation sample (101 PD patients and 107 HCs).

View Article and Find Full Text PDF

Solid-state batteries (SSBs) are considered as one of the most promising candidates for the next-generation energy-storage technology, because they simultaneously exhibit high safety, high energy density, and wide operating temperature range. The replacement of liquid electrolytes with solid electrolytes produces numerous solid-solid interfaces within the SSBs. A thorough understanding on the roles of these interfaces is indispensable for the rational performance optimization.

View Article and Find Full Text PDF

Objective: The purpose of this study was to investigate the role of aberrant DNA methylation of hypothalamic-pituitary-adrenal (HPA) axis-related genes (CRHR1, CRHR2, CRH, FKBP5, HSP90AA1, NR3C1, and POMC) in panic disorder (PD) development. We investigated the correlation among gene methylation levels, adrenocorticotropic hormone (ACTH), cortisol, and PD severity in patients.

Methods: We compared the methylation levels of HPA axis-related genes between 178 patients with PD and 184 healthy controls using MethylTarget.

View Article and Find Full Text PDF

Fulminant hepatic failure (FHF) is a potentially fatal liver disease that is associated with intrahepatic infiltration of inflammatory cells. As the receptor of polyunsaturated long chain fatty acids, GPR120 can regulate cell differentiation, proliferation, metabolism, and immune response. However, whether GPR120 is involved in FHF remains unknown.

View Article and Find Full Text PDF

Lessons Learned: The combination of anlotinib and S-1 exhibited good antitumor activity in third- or later-line treatment for stage IV non-small cell lung cancer (NSCLC). Combination therapy of anlotinib with S-1 has manageable toxicities in patients with NSCLC.

Background: This study aimed to evaluate the efficacy and safety of anlotinib combined with S-1 as a third- or later-line treatment for patients with stage IV non-small cell lung cancer (NSCLC).

View Article and Find Full Text PDF

Background & Aims: Fulminant hepatitis (FH) is a clinical syndrome characterized by sudden and severe liver dysfunction. Dot1L, a histone methyltransferase, is implicated in various physiologic and pathologic processes, including transcription regulation and leukemia. However, the role of Dot1L in regulating inflammatory responses during FH remains elusive.

View Article and Find Full Text PDF
Article Synopsis
  • Chemoresistance in advanced gastric cancer is a significant issue, impacting the effectiveness of chemotherapy treatments, particularly concerning the long non-coding RNA (LncRNA) BANCR, which has unclear roles in this context.
  • The study measured LncRNA BANCR expression in gastric cancer samples and found that its overexpression contributed to increased resistance to cisplatin, a common chemotherapy drug.
  • The research demonstrated that inhibiting BANCR effectively reduced tumor growth and cisplatin resistance by impacting the ERK1/2 signaling pathway, suggesting a potential new strategy for gastric cancer treatment.
View Article and Find Full Text PDF

This study aimed to investigate the specificity and sensitivity of oral meglumine diatrizoate esophagogram in screening for esophageal fistula during radiotherapy or chemoradiotherapy for esophageal cancer and determine if early detection and intervention could improve the prognosis of esophageal fistulas. Esophageal cancer patients undergoing radiotherapy or chemoradiotherapy were included. Weekly oral meglumine diatrizoate esophagograms were performed to screen for esophageal fistulas during radiotherapy.

View Article and Find Full Text PDF

An excessive amount of adipose tissue surrounding the blood vessels (perivascular adipose tissue, also known as PVAT) is associated with a high risk of cardiovascular disease. ADSCs derived from different adipose tissues show distinct features, and those from the PVAT have not been well characterized. In a recent study, we reported that some ADSCs in the periaortic arch adipose tissue (PAAT) descend from the neural crest cells (NCCs), a transient population of migratory cells originating from the ectoderm.

View Article and Find Full Text PDF

Deoxynivalenol (DON) is a highly abundant mycotoxin that exerts many adverse effects on humans and animals. Much effort has been made to control DON in the past, and bio-transformation has emerged as the most promising method. However, useful and effective application of bacterial bio-transformation for the purpose of inhibiting DON remains urgently needed.

View Article and Find Full Text PDF

Background: A proportion of patients with stage IV non-small-cell lung cancer (NSCLC) is predicted to receive third-line treatment. However, currently no standard third-line treatment for NSCLC is available. Anlotinib is an oral, multi-targeted tyrosine kinase (TK) receptor inhibitor, which was approved as a third-line treatment for stage IV NSCLC in China on May 9, 2018.

View Article and Find Full Text PDF